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(PSYCHEDELICS)

SEROTONERGIC CLASSICAL HALLUCINOGENS

WHAT DO PSYCHEDELICS TO DO MY BRAIN?

Psychedelics show their effects mainly through the 5-HT (serotonin) system.  They are 5-HT2A  receptor agonists, which activate serotonergic and dopaminergic activity in the brain (specifically in the dorsal raphe nucleus and VTA).  They are implicated in mood and anxiety regulation.  Psychedelics also have effects on the dopaminergic system.  These drugs significantly alter people's perception of reality and cause several mind-altering effects.

Types of Psychedelics and Their Effects

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Researcher

Psychedelic Research

Glossary

Receptor Agonist - A chemical that binds to and activates receptors

Receptor Antagonist - Chemical that binds to receptor, stopping it from producing a response

Serotonin (5HT) - Neurotransmitter/ hormone that regulates activities like mood, behavior, memory, sleep, etc.

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